概述

  • 产品名称Anti-SV2A抗体
    参阅全部 SV2A 一抗
  • 描述
    山羊多克隆抗体to SV2A
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Horse, Cow, Dog, Human, Pig, Chimpanzee, Zebrafish, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-TVELYPSDKRTTA

    , corresponding to internal sequence amino acids 673-685 of Human SV2A (NP_055664.2)

  • 阳性对照
    • Rat brain lysate.

性能

应用

Our Abpromise guarantee covers the use of ab77177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: antibody detection limit dilution 1/64000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 83 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.
    • 序列相似性Belongs to the major facilitator superfamily.
    • 翻译后修饰Phosphorylation by CK1 of the N-terminal cytoplasmic domain regulates interaction with SYT1.
      N-glycosylated.
    • 细胞定位Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.
    • Information by UniProt
    • 数据库链接
    • 别名
      • KIAA0736 antibody
      • OTTHUMP00000014065 antibody
      • SV2 antibody
      • Sv2a antibody
      • SV2A_HUMAN antibody
      • Synaptic vesicle glycoprotein 2 antibody
      • Synaptic vesicle glycoprotein 2A antibody
      • Synaptic vesicle protein 2a antibody
      see all

    Anti-SV2A antibody 图像

    • Anti-SV2A antibody (ab77177) at 0.3 µg/ml + rat brain lysate in RIPA buffer at 35 µg

      Predicted band size : 83 kDa
      Observed band size : 80 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 28 kDa. We are unsure as to the identity of these extra bands.

    Anti-SV2A antibody (ab77177)参考文献

    ab77177 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"