概述

  • 产品名称Anti-SUV420h1抗体
    参阅全部 SUV420h1 一抗
  • 描述
    兔多克隆抗体to SUV420h1
  • 经测试应用适用于: ICC, WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptides derived from internal domains of Human SUV420h1.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: None
    Constituents: Whole serum
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab104875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 99 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
  • 序列相似性Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
    Contains 1 SET domain.
  • 细胞定位Nucleus. Chromosome. Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity).
  • Information by UniProt
  • 数据库链接
  • 别名
    • CGI 85 antibody
    • CGI85 antibody
    • Histone-lysine N-methyltransferase KMT5B antibody
    • KMT5B antibody
    • KMT5B_HUMAN antibody
    • Lysine N-methyltransferase 5B antibody
    • Lysine-specific methyltransferase 5B antibody
    • MGC118906 antibody
    • MGC118909 antibody
    • MGC21161 antibody
    • MGC703 antibody
    • Su(var)4-20 homolog 1 antibody
    • Suppressor of variegation 4 20 homolog 1 antibody
    • Suppressor of variegation 4-20 homolog 1 antibody
    • Suv4-20h1 antibody
    see all

Anti-SUV420h1 antibody (ab104875)参考文献

ab104875 has not yet been referenced specifically in any publications.

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