Anti-Surfactant protein D抗体[VI F11] (ab15688)


  • 产品名称
    Anti-Surfactant protein D抗体[VI F11]
    参阅全部 Surfactant protein D 一抗
  • 描述
    小鼠单克隆抗体[VI F11] to Surfactant protein D
  • 特异性
    Alveolar type III cells stain negative. No reaction on rat skin, colon, kidney and liver.
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Purified rat surfactant protein D from bronchoalveolar lavage.

  • 表位
    The VIF11 epitope is localized in the lectin domain of Surfactant protein D.
  • 阳性对照
    • Alveolar type II cells, alveolar macrophages, two types of Clara cells SP-A+ and SP-A-.



Our Abpromise guarantee covers the use of ab15688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明
    ELISA: Use at a concentration of 2 µg/ml.
    IHC-P: 1/20 (human) - 1/400 (rat).
    WB: Use at an assay dependent dilution. Predicted molecular weight: 43 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
    • 序列相似性
      Belongs to the SFTPD family.
      Contains 1 C-type lectin domain.
      Contains 1 collagen-like domain.
    • 翻译后修饰
      The N-terminus is blocked.
      Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
    • 细胞定位
      Secreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.
    • Information by UniProt
    • 数据库链接
    • 别名
      • COLEC 7 antibody
      • COLEC7 antibody
      • Collectin-7 antibody
      • Collectin7 antibody
      • Lung surfactant protein D antibody
      • PSP D antibody
      • PSP-D antibody
      • PSP-D Surfactant protein D antibody
      • PSPD antibody
      • Pulmonary surfactant apoprotein antibody
      • Pulmonary surfactant associated protein D antibody
      • Pulmonary surfactant associated protein PSP-D antibody
      • Pulmonary surfactant-associated protein D antibody
      • SFTP 4 antibody
      • SFTP4 antibody
      • SFTPD antibody
      • SFTPD_HUMAN antibody
      • SP D antibody
      • SP-D antibody
      • Surfactant associated protein pulmonary 4 antibody
      • Surfactant pulmonary associated protein D antibody
      see all

    Anti-Surfactant protein D antibody [VI F11] (ab15688)参考文献

    This product has been referenced in:
    • Yadav AK  et al. Differential expression of collectins in human placenta and role in inflammation during spontaneous labor. PLoS One 9:e108815 (2014). WB ; Human . Read more (PubMed: 25303045) »
    • Kasper M  et al. Monoclonal antibodies to surfactant protein D: evaluation of immunoreactivity in normal rat lung and in a radiation-induced fibrosis model. Exp Lung Res 21:577-88 (1995). Read more (PubMed: 7588444) »

    See all 2 Publications for this product

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