概述

  • 产品名称Anti-Superoxide Dismutase 3抗体
    参阅全部 Superoxide Dismutase 3 一抗
  • 描述
    兔多克隆抗体to Superoxide Dismutase 3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Rabbit
  • 免疫原

    Synthetic peptide derived from Superoxide Dismutase 3

  • 阳性对照
    • Rat and mouse Lung Tissue Extract; Human Superoxide Dismutase 3 Protein.

性能

应用

Our Abpromise guarantee covers the use of ab83108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 35 kDa (predicted molecular weight: 26 kDa).

靶标

  • 功能Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
  • 组织特异性Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
  • 序列相似性Belongs to the Cu-Zn superoxide dismutase family.
  • 细胞定位Secreted > extracellular space. 99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC SOD antibody
    • EC-SOD antibody
    • Extracellular superoxide dismutase [Cu Zn] antibody
    • Extracellular superoxide dismutase [Cu-Zn] antibody
    • Extracellular superoxide dismutase antibody
    • Extracellular superoxide dismutase precursor antibody
    • MGC20077 antibody
    • SOD 3 antibody
    • SOD3 antibody
    • SODE_HUMAN antibody
    • Superoxide dismutase 3 extracellular antibody
    see all

Anti-Superoxide Dismutase 3 antibody 图像

  • All lanes : Anti-Superoxide Dismutase 3 antibody (ab83108) at 1/1000 dilution

    Lane 1 : Rat lung tissue extract
    Lane 2 : Mouse lung tissue extract
    Lane 3 : Human Superoxide Dismutase 3 protein

    Developed using the ECL technique

    Predicted band size : 26 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 40 kDa (possible glycosylated form),60 kDa (possible dimer).

Anti-Superoxide Dismutase 3 antibody (ab83108)参考文献

This product has been referenced in:
  • Ramiro-Diaz JM  et al. Mechanisms of NFATc3 activation by increased superoxide and reduced hydrogen peroxide in pulmonary arterial smooth muscle. Am J Physiol Cell Physiol 307:C928-38 (2014). Read more (PubMed: 25163518) »

See 1 Publication for this product

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