概述

  • 产品名称Anti-SUN1抗体
    参阅全部 SUN1 一抗
  • 描述
    小鼠多克隆抗体to SUN1
  • 特异性This antibody is reactive against mammalian transfected lysate.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    SUN1 (AAH13613, 1 a.a. ~ 258 a.a) full-length human protein.

  • 阳性对照
    • SUN1 transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab67999 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 35 kDa (predicted molecular weight: 90 kDa).

靶标

  • 功能Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs).
  • 序列相似性Contains 1 SUN domain.
  • 结构域The SUN domain may play a role in the nuclear anchoring and/or migration.
  • 细胞定位Nucleus inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Protein unc-84 homolog A antibody
    • Sad1 and UNC84 domain containing 1 antibody
    • Sad1/unc 84 protein like 1 antibody
    • Sad1/unc-84 protein-like 1 antibody
    • Sun domain-containing protein 1 antibody
    • Sun1 antibody
    • SUN1_HUMAN antibody
    • UNC 84 homolog A (C elegans) antibody
    • UNC 84A antibody
    • UNC84 A antibody
    • UNC84 antibody
    • UNC84 homolog A (C elegans) antibody
    • UNC84A antibody
    see all

Anti-SUN1 antibody 图像

  • All lanes : Anti-SUN1 antibody (ab67999) at 1/500 dilution

    Lane 1 : SUN1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 90 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)

Anti-SUN1 antibody (ab67999)参考文献

ab67999 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application Western blot
Loading amount 50 µg
Gel Running Conditions Reduced Denaturing (4-12%)
Sample Human Cell lysate - whole cell (HeLa, RPE-1)
Specification HeLa, RPE-1
Blocking step Milk as blocking agent for 16 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 4°C
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提交于 Jul 09 2013

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