概述

  • 产品名称Anti-SULT2B1抗体
    参阅全部 SULT2B1 一抗
  • 描述
    小鼠单克隆抗体to SULT2B1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS, corresponding to amino acids 1-90 of human SULT2B1 protein (NP_814444) with a proprietary tag.

  • 阳性对照
    • MCF-7 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab88085 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 41 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol.
  • 组织特异性Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung.
  • 序列相似性Belongs to the sulfotransferase 1 family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alcohol sulfotransferase antibody
    • EC 2.8.2.2 antibody
    • HSST2 antibody
    • Hydroxysteroid sulfotransferase 2 antibody
    • ST2B1 antibody
    • ST2B1_HUMAN antibody
    • Sulfotransferase 2B1 antibody
    • Sulfotransferase family cytosolic 2B member 1 antibody
    • SULT2B1 antibody
    • SULT2B1a antibody
    • SULT2B1b antibody
    see all

Anti-SULT2B1 antibody 图像

  • Anti-SULT2B1 antibody (ab88085) at 5 µg/ml + the immunogen at 0.2 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Predicted band size : 41 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)
  • Anti-SULT2B1 antibody (ab88085) at 5 µg/ml + MCF-7 cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 41 kDa
    Observed band size : 41 kDa

Anti-SULT2B1 antibody (ab88085)参考文献

This product has been referenced in:
  • Vickman RE  et al. Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer. Mol Cancer Res 14:776-86 (2016). Read more (PubMed: 27341831) »

See 1 Publication for this product

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