Anti-SUCLG1抗体(ab97867)
Key features and details
- Rabbit polyclonal to SUCLG1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SUCLG1抗体
参阅全部 SUCLG1 一抗 -
描述
兔多克隆抗体to SUCLG1 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Zebrafish -
免疫原
Recombinant fragment, corresponding to a region within amino acids 1-316 of Human SUCLG1 (NP_003840).
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阳性对照
- A431 whole cell lysate; A549 cells; 293T, H1299, HeLaS3, HepG2, Molt-4 and Raji cell lines
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97867于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 36 kDa.
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|
ICC/IF |
1/100 - 1/200.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 36 kDa. |
ICC/IF
1/100 - 1/200. |
靶标
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功能
Catalyzes the ATP- or GTP-dependent ligation of succinate and CoA to form succinyl-CoA. The nature of the beta subunit determines the nucleotide specificity. -
通路
Carbohydrate metabolism; tricarboxylic acid cycle. -
疾病相关
Mitochondrial DNA depletion syndrome 9 -
序列相似性
Belongs to the succinate/malate CoA ligase alpha subunit family. -
细胞定位
Mitochondrion. - Information by UniProt
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数据库链接
- Entrez Gene: 509983 Cow
- Entrez Gene: 8802 Human
- Entrez Gene: 56451 Mouse
- Entrez Gene: 114597 Rat
- Omim: 611224 Human
- SwissProt: Q58DR8 Cow
- SwissProt: P53597 Human
- SwissProt: Q9WUM5 Mouse
see all -
别名
- FLJ21114 antibody
- FLJ43513 antibody
- GALPHA antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab97867 被引用在 3 文献中.
- Dobolyi A et al. Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation. Brain Struct Funct 225:639-667 (2020). PubMed: 31982949
- Ali HR et al. Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy. J Mol Cell Cardiol 138:304-317 (2020). PubMed: 31836543
- Xu Z et al. Proteomics Analysis Reveals Abnormal Electron Transport and Excessive Oxidative Stress Cause Mitochondrial Dysfunction in Placental Tissues of Early-Onset Preeclampsia. Proteomics Clin Appl 12:e1700165 (2018). PubMed: 29676857