Anti-Substance P抗体[M09205] (ab7340)

概述

  • 产品名称
    Anti-Substance P抗体[M09205]
    参阅全部 Substance P 一抗
  • 描述
    大鼠单克隆抗体[M09205] to Substance P
  • 经测试应用
    适用于: IHC-Fr, IHC-FoFrmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Substance-P conjugated to BSA.

  • 常规说明


    Substance P belongs to the tachykinin family. These are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

性能

应用

Our Abpromise guarantee covers the use of ab7340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent dilution.
IHC-FoFr Use at an assay dependent concentration. PubMed: 21294877

靶标

  • 功能
    Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
  • 序列相似性
    Belongs to the tachykinin family.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C-terminal-flanking peptide antibody
    • Hs.2563 antibody
    • neurokinin 1 antibody
    • neurokinin 2 antibody
    • neurokinin A antibody
    • neurokinin alpha antibody
    • Neuromedin L antibody
    • neuropeptide gamma antibody
    • neuropeptide K antibody
    • NK2 antibody
    • NKA antibody
    • NKNA antibody
    • NPK antibody
    • PPT antibody
    • preprotachykinin antibody
    • protachykinin antibody
    • protachykinin-1 antibody
    • Substance K antibody
    • SubstanceP antibody
    • TAC1 antibody
    • TAC2 antibody
    • TAC2, formerly antibody
    • Tachykinin 1 antibody
    • tachykinin 2 antibody
    • tachykinin 2, formerly antibody
    • Tachykinin precursor 1 antibody
    • tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) antibody
    • Tachykinin1 antibody
    • TKN1_HUMAN antibody
    see all

Anti-Substance P antibody [M09205] 图像

  • Immunohistochemical analysis of frozen neonatal murine DRG explants, staining Substance P with ab7340 at 1/200 dilution.

    Tissue was fixed in paraformaldehyde, cut into 10 µm sections, permeabilized with 0.1% SDS for 5 mins and incubated in 10% foetal calf serum in TBST for 10 mins. Sections were incubated with primary antibody overnight before incubating with Texas Red-conjugated goat anti-rat secondary antibody (1/250) for 40 minutes at room temperature.

Anti-Substance P antibody [M09205] (ab7340)参考文献

This product has been referenced in:
  • Petto C  et al. Architecture and Chemical Coding of the Inner and Outer Submucous Plexus in the Colon of Piglets. PLoS One 10:e0133350 (2015). Read more (PubMed: 26230272) »
  • George L  et al. Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons. Proc Natl Acad Sci U S A 110:18698-703 (2013). Mouse . Read more (PubMed: 24173031) »

See all 4 Publications for this product

Product Wall

Application
Immunohistochemistry (Frozen sections)
Sample
Human Tissue sections (nasal mucosa)
Specification
nasal mucosa
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 24°C
Fixative
Paraformaldehyde
Username

Mr. Duc Dung Le

Verified customer

提交于 Jun 10 2016

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Blocking step
Serum as blocking agent for 45 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Antigen retrieval step
None
Sample
Mouse Tissue sections (Trigeminal ganglion)
Specification
Trigeminal ganglion
Permeabilization
No
Fixative
Zamboni
Username

Mr. Duc Dung Le

Verified customer

提交于 Apr 10 2015



ab7340 is not a purified antibody, which would typically be suspended in a colorless buffer such as PBS. Rather ab7340 is an unpurified tissue culture supernatant. Tissue culture medium typically has a light purple/pinkish hue so the color yo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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