概述

  • 产品名称Anti-Substance P抗体
    参阅全部 Substance P 一抗
  • 描述
    兔多克隆抗体to Substance P
  • 经测试应用适用于: ICC/IF, IHC-Frmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Synthetic peptide corresponding to Rat Substance P conjugated to Keyhole Limpet Haemocyanin (KLH).

  • 阳性对照
    • Rat spinal cord dorsal horn

性能

应用

Our Abpromise guarantee covers the use of ab67006 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF
IHC-Fr
  • 应用说明ICC/IF: 1/300 - 1/500.
    IHC-Fr: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    The Substance P antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates significant positive labeling of rat substantia nigra and spinal cord using indirect immunofluorescent techniques. Specificity was demonstrated using soluble pre-adsorption with the peptides in question at a final concentration of 10 µg of peptide per mL of diluted antiserum. Immunolabeling was completely abolished by pre-adsorption with Substance P. Pre-adsorption with the following peptides resulted in no reduction of immunostaining: neurokinin A, neurokinin B, somatostatin and neuropeptide K.
  • 靶标

    • 功能Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
    • 序列相似性Belongs to the tachykinin family.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C-terminal-flanking peptide antibody
      • Hs.2563 antibody
      • neurokinin 1 antibody
      • neurokinin 2 antibody
      • neurokinin A antibody
      • neurokinin alpha antibody
      • Neuromedin L antibody
      • neuropeptide gamma antibody
      • neuropeptide K antibody
      • NK2 antibody
      • NKA antibody
      • NKNA antibody
      • NPK antibody
      • PPT antibody
      • preprotachykinin antibody
      • protachykinin antibody
      • protachykinin-1 antibody
      • Substance K antibody
      • SubstanceP antibody
      • TAC1 antibody
      • TAC2 antibody
      • TAC2, formerly antibody
      • Tachykinin 1 antibody
      • tachykinin 2 antibody
      • tachykinin 2, formerly antibody
      • Tachykinin precursor 1 antibody
      • tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) antibody
      • Tachykinin1 antibody
      • TKN1_HUMAN antibody
      see all

    Anti-Substance P antibody 图像

    • Detection of Substance P in rat spinal cord dorsal horn with ab67006 (25 um sections).

    Anti-Substance P antibody (ab67006)参考文献

    This product has been referenced in:
    • Herrity AN  et al. The effect of spinal cord injury on the neurochemical properties of vagal sensory neurons. Am J Physiol Regul Integr Comp Physiol 308:R1021-33 (2015). Read more (PubMed: 25855310) »

    See 1 Publication for this product

    Product Wall

    Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Sample Rat Tissue sections (skin)
    Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Citrate Buffer
    Permeabilization No
    Specification skin
    Blocking step Background Punisher as blocking agent for 30 minute(s) · Concentration: 100% · Temperature: 22°C
    Fixative Paraformaldehyde
    Username

    Ms. Elisabete de Cassia do Carmo

    Verified customer

    提交于 Aug 17 2015

    ab67006 is designed to recognize the mature or processed form of Substance P.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"