概述

  • 产品名称
    Anti-Streptolysin抗体[6D11]
  • 描述
    小鼠单克隆抗体[6D11] to Streptolysin
  • 特异性
    ab23501 is specific for oxidized streptolysin but cross reacts with untreated streptolysin
  • 经测试应用
    适用于: ELISA, WB, ICC/IFmore details
  • 免疫原

    Cysteine chloride oxidized streptolysin.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    单克隆
  • 克隆编号
    6D11
  • 骨髓瘤
    x63-Ag8.653
  • 同种型
    IgG1
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab23501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/400.
WB Use at an assay dependent concentration. PubMed: 21693578
ICC/IF Use at an assay dependent concentration. PubMed: 21693578

靶标

  • 相关性
    Bacteria of the Streptococcus genera produce the exotoxin streptolysin. Anti-streptolysin antibody titers in patients are measured as a marker of inflammation. Streptolysin is also an important tool in cell biology due to its hemolytic activity and the ability to permeabilize plasma membranes. Sulfhydryl-activated toxin. Is able to lyse cholesterol containing membranes. Can be reversibly inactivated by oxidation. Cholesterol is the receptor for the binding of these toxins to eukaryotic cell membranes.
  • 细胞定位
    Secreted
  • 别名
    • Slo antibody
    • Streptolysin O antibody
    • Thiol activated cytolysin antibody

Anti-Streptolysin antibody [6D11] (ab23501)参考文献

This product has been referenced in:
  • Horiuchi T  et al. Floating chip mounting system driven by repulsive force of permanent magnets for multiple on-site SPR immunoassay measurements. Sensors (Basel) 12:13964-84 (2012). Read more (PubMed: 23202030) »
  • Horiuchi T  et al. Passive fluidic chip composed of integrated vertical capillary tubes developed for on-site SPR immunoassay analysis targeting real samples. Sensors (Basel) 12:7095-108 (2012). Read more (PubMed: 22969339) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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