概述

  • 产品名称Anti-Streptolysin抗体[6D11]
  • 描述
    小鼠单克隆抗体[6D11] to Streptolysin
  • 特异性ab23501 is specific for oxidized streptolysin but cross reacts with untreated streptolysin
  • 经测试应用适用于: ELISA, WB, ICC/IFmore details
  • 免疫原

    Cysteine chloride oxidized streptolysin.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号6D11
  • 骨髓瘤x63-Ag8.653
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab23501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/400.
WB Use at an assay dependent concentration. PubMed: 21693578
ICC/IF Use at an assay dependent concentration. PubMed: 21693578

靶标

  • 相关性Bacteria of the Streptococcus genera produce the exotoxin streptolysin. Anti-streptolysin antibody titers in patients are measured as a marker of inflammation. Streptolysin is also an important tool in cell biology due to its hemolytic activity and the ability to permeabilize plasma membranes. Sulfhydryl-activated toxin. Is able to lyse cholesterol containing membranes. Can be reversibly inactivated by oxidation. Cholesterol is the receptor for the binding of these toxins to eukaryotic cell membranes.
  • 细胞定位Secreted
  • 别名
    • Slo antibody
    • Streptolysin O antibody
    • Thiol activated cytolysin antibody

Anti-Streptolysin antibody [6D11] (ab23501)参考文献

This product has been referenced in:
  • Keyel PA  et al. Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane. J Cell Sci 124:2414-23 (2011). ICC/IF, WB . Read more (PubMed: 21693578) »

See 1 Publication for this product

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