Anti-Streptolysin抗体[6D11] (ab23501)
Key features and details
- Mouse monoclonal [6D11] to Streptolysin
- Suitable for: ELISA
- Reacts with: Streptococcus
- Isotype: IgG1
概述
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产品名称
Anti-Streptolysin抗体[6D11] -
描述
小鼠单克隆抗体[6D11] to Streptolysin -
宿主
Mouse -
特异性
ab23501 is specific for oxidized streptolysin but cross reacts with untreated streptolysin -
经测试应用
适用于: ELISAmore details -
种属反应性
与反应: Streptococcus -
免疫原
Cysteine chloride oxidized streptolysin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
6D11 -
骨髓瘤
x63-Ag8.653 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab23501于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
1/400.
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说明 |
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ELISA
1/400. |
靶标
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相关性
Bacteria of the Streptococcus genera produce the exotoxin streptolysin. Anti-streptolysin antibody titers in patients are measured as a marker of inflammation. Streptolysin is also an important tool in cell biology due to its hemolytic activity and the ability to permeabilize plasma membranes. Sulfhydryl-activated toxin. Is able to lyse cholesterol containing membranes. Can be reversibly inactivated by oxidation. Cholesterol is the receptor for the binding of these toxins to eukaryotic cell membranes. -
细胞定位
Secreted -
别名
- Slo antibody
- Streptolysin O antibody
- Thiol activated cytolysin antibody
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab23501 被引用在 4 文献中.
- Lin CY et al. Autophagy Receptor Tollip Facilitates Bacterial Autophagy by Recruiting Galectin-7 in Response to Group A Streptococcus Infection. Front Cell Infect Microbiol 10:583137 (2020). PubMed: 33425778
- Horiuchi T et al. Floating chip mounting system driven by repulsive force of permanent magnets for multiple on-site SPR immunoassay measurements. Sensors (Basel) 12:13964-84 (2012). PubMed: 23202030
- Horiuchi T et al. Passive fluidic chip composed of integrated vertical capillary tubes developed for on-site SPR immunoassay analysis targeting real samples. Sensors (Basel) 12:7095-108 (2012). PubMed: 22969339
- Keyel PA et al. Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane. J Cell Sci 124:2414-23 (2011). ICC/IF, WB . PubMed: 21693578