The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ID: Use at an assay dependent dilution.
Ie: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Streptococcus mutans is a Gram positive, facultatively anaerobic bacteria commonly found in the human oral cavity and is a significant contributor to tooth decay. S. mutans plays a major role in tooth decay, metabolizing sucrose to lactic acid. The acidic environment created in the mouth by this process is what causes the highly mineralized tooth enamel to be vulnerable to decay. S. mutans is one of a few specialized organisms equipped with receptors for adhesion to the surface of teeth. Sucrose is utilized by S. mutans to produce a sticky, extracellular, dextran based polysaccharide that allows them to cohere to each other forming plaque. S. mutans produces dextran via the enzyme dextransucrase using sucrose as a substrate.
Dong G et al. Regulated proteolysis of the alternative sigma factor SigX in Streptococcus mutans: implication in the escape from competence. BMC Microbiol14:183 (2014).
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