概述

  • 产品名称Anti-STRC抗体
    参阅全部 STRC 一抗
  • 描述
    兔多克隆抗体to STRC
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    antigen sequence, corresponding to amino acids 411-541 of Human STRC.

  • 阳性对照
    • Human bone marrow tissue; RT 4 and U 251 MG cell lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab121485 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

靶标

  • 疾病相关Defects in STRC are the cause of deafness autosomal recessive type 16 (DFNB16) [MIM:603720]. DFNB16 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
    Defects in STRC are a cause of deafness-infertility syndrome (DIS) [MIM:611102]. DIS is characterized by deafness and infertility and is caused by large contiguous gene deletions at 15q15.3 that removes both STRC and CATSPER2 genes.
  • 序列相似性Belongs to the stereocilin family.
  • 细胞定位Cell surface. Associated with the hair bundle.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DFNB16 antibody
    • Stereocilin antibody
    • STRC antibody
    • STRC_HUMAN antibody

Anti-STRC antibody 图像

  • ab121485, at 1/450 dilution, staining STRC in paraffin-embedded Human bone marrow tissue by Immunohistochemistry, showing strong cytoplasmic positivity in Megakaryocytes.
  • All lanes : Anti-STRC antibody (ab121485) at 1/250 dilution

    Lane 1 : RT 4 cell lysate
    Lane 2 : U 251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique

Anti-STRC antibody (ab121485)参考文献

ab121485 has not yet been referenced specifically in any publications.

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