STO-609 acetate,CaM-KK抑制剂(ab141591)
Key features and details
- Potent, competitive, selective and cell-permeable inhibitor of CaM-KK
- CAS Number: 1173022-21-3
- Purity: > 98%
Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
STO-609 acetate,CaM-KK抑制剂 -
描述
Potent,competitive,selective and cell-permeable抑制剂of CaM-KK -
生物学描述
Potent, competitive, selective and cell-permeable inhibitor of CaM-KK (Ki values are0.21 µM and 40 nM for CaM-KKα and CaM-KKβ respectively). Potent, competitive AhR agonist (EC50 = 43 nM). Active in vivo. -
纯度
> 98% -
CAS编号
1173022-21-3 -
化学结构
性能
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化学名称
7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate
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分子量
374.35 -
分子式
C19H10N2O3.C2H4O2 -
PubChem识别号
16760660 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 25 mM
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处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)O.C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (3)
ab141591 被引用在 3 文献中.
- Ferdowsi PV et al. Capsaicin and Zinc Promote Glucose Uptake in C2C12 Skeletal Muscle Cells through a Common Calcium Signalling Pathway. Int J Mol Sci 23:N/A (2022). PubMed: 35216322
- Xie B et al. Induction of autophagy and suppression of type I IFN secretion by CSFV. Autophagy 17:925-947 (2021). PubMed: 32160078
- LeBlond ND et al. Foam Cell Induction Activates AMPK But Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis. Int J Mol Sci 21:N/A (2020). PubMed: 33261140