Anti-Steroid sulfatase抗体(ab83668)

概述

  • 产品名称Anti-Steroid sulfatase抗体
    参阅全部 Steroid sulfatase 一抗
  • 描述
    兔多克隆抗体to Steroid sulfatase
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Horse, Guinea pig, Cow, Pig, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 396-445 (EPTSNMDIFP TVAKLAGAPL PEDRIIDGRD LMPLLEGKSQ RSDHEFLFHY) of Human Steroid sulfatase (NP_000342).

  • 阳性对照
    • Human Placenta lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab83668 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).Can be blocked with Steroid sulfatase peptide (ab199997). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Conversion of sulfated steroid precursors to estrogens during pregnancy.
  • 疾病相关Defects in STS are the cause of ichthyosis X-linked (IXL) [MIM:308100]. Ichthyosis X-linked is a keratinization disorder manifesting with mild erythroderma and generalized exfoliation of the skin within a few weeks after birth. Affected boys later develop large, polygonal, dark brown scales, especially on the neck, extremities, trunk, and buttocks.
  • 序列相似性Belongs to the sulfatase family.
  • 翻译后修饰The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARSC antibody
    • ARSC1 antibody
    • Arylsulfatase C antibody
    • Arylsulfatase C isozyme S antibody
    • ASC antibody
    • EC 3.1.6.2 antibody
    • ES antibody
    • Estrone sulfatase antibody
    • SSDD antibody
    • Steroid sulfatase (microsomal) antibody
    • Steroid sulfatase (microsomal) arylsulfatase C isozyme S antibody
    • Steroid sulfatase antibody
    • Steryl sulfatase antibody
    • Steryl sulfatase precursor antibody
    • Steryl sulfate sulfohydrolase antibody
    • Steryl-sulfatase antibody
    • Steryl-sulfate sulfohydrolase antibody
    • STS antibody
    • STS_HUMAN antibody
    see all

Anti-Steroid sulfatase antibody 图像

  • Anti-Steroid sulfatase antibody (ab83668) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human placenta lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 63 kDa
    Observed band size : 63 kDa

Anti-Steroid sulfatase antibody (ab83668)参考文献

ab83668 has not yet been referenced specifically in any publications.

Product Wall

I have been in contact with the lab and they have agreed to add this product to the catalogue.

The peptide for ab83668 has been added to the catalogue under reference number ab199997, Steroid sulfatase peptide.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"