概述

  • 产品名称Anti-STEAP4抗体
    参阅全部 STEAP4 一抗
  • 描述
    山羊多克隆抗体to STEAP4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide:

    CVDNTLTRIRQGWERN

    , corresponding to C terminal amino acids 441-456 of Human STEAP4

  • 阳性对照
    • Human Adipose lysate.

性能

应用

Our Abpromise guarantee covers the use of ab63967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明Peptide ELISA: antibody detection limit dilution: 1/4000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.
    • 组织特异性Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.
    • 序列相似性Belongs to the STEAP family.
      Contains 1 ferric oxidoreductase domain.
    • 细胞定位Cell membrane. Golgi apparatus membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • alpha-induced protein 9 antibody
      • Metalloreductase STEAP4 antibody
      • six transmembrane prostate protein 2 antibody
      • Six-transmembrane epithelial antigen of prostate 4 antibody
      • SixTransMembrane protein of prostate 2 antibody
      • STAMP 2 antibody
      • STAMP2 antibody
      • STEA4_HUMAN antibody
      • STEAP 4 antibody
      • STEAP family member 4 antibody
      • STEAP4 antibody
      • TIARP antibody
      • TNFAIP 9 antibody
      • TNFAIP9 antibody
      • Tumor necrosis factor antibody
      • tumor necrosis factor, alpha-induced protein 9 antibody
      • tumor necrosis-alpha-induced adipose-related protein antibody
      see all

    Anti-STEAP4 antibody 图像

    • Anti-STEAP4 antibody (ab63967) at 0.3 µg/ml + Human Adipose lysate at 35 µg

      Predicted band size : 52 kDa
      Observed band size : 52 kDa

    Anti-STEAP4 antibody (ab63967)参考文献

    ab63967 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"