概述

  • 产品名称Anti-STEAP4抗体
    参阅全部 STEAP4 一抗
  • 描述
    兔多克隆抗体to STEAP4
  • 经测试应用适用于: ELISA, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH from Human STEAP4.

  • 阳性对照
    • Human Liver and Skin tissues; HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab113230 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/20000.
IHC-P Use a concentration of 10 µg/ml.
ICC/IF 1/100 - 1/500.

靶标

  • 功能Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.
  • 组织特异性Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.
  • 序列相似性Belongs to the STEAP family.
    Contains 1 ferric oxidoreductase domain.
  • 细胞定位Cell membrane. Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • alpha-induced protein 9 antibody
    • Metalloreductase STEAP4 antibody
    • six transmembrane prostate protein 2 antibody
    • Six-transmembrane epithelial antigen of prostate 4 antibody
    • SixTransMembrane protein of prostate 2 antibody
    • STAMP 2 antibody
    • STAMP2 antibody
    • STEA4_HUMAN antibody
    • STEAP 4 antibody
    • STEAP family member 4 antibody
    • STEAP4 antibody
    • TIARP antibody
    • TNFAIP 9 antibody
    • TNFAIP9 antibody
    • Tumor necrosis factor antibody
    • tumor necrosis factor, alpha-induced protein 9 antibody
    • tumor necrosis-alpha-induced adipose-related protein antibody
    see all

Anti-STEAP4 antibody 图像

  • ab113230, at 10µg/ml, staining STEAP4 in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.
  • ab113230, at 10µg/ml, staining STEAP4 in Formalin-fixed, Paraffin-embedded Human Skin tissue by Immunohistochemistry.
  • ab113230 at 1/100 dilution staining STEAP4 in HeLa cells by Immunofluorescence. The image on the right is treated with the synthesized peptide.

Anti-STEAP4 antibody (ab113230)参考文献

ab113230 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113230.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"