概述

描述

  • 性质Synthetic

技术指标

Our Abpromise guarantee covers the use of ab110446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium azide
    Constituent: 0.1% BSA

常规信息

  • 别名
    • Double stranded RNA binding protein Staufen homolog
    • Double stranded RNA binding protein Staufen homolog 1
    • Double-stranded RNA-binding protein Staufen homolog 1
    • FLJ25010
    • MGC124588
    • STAU
    • STAU1
    • STAU1_HUMAN
    • staufen
    • Staufen RNA binding protein (Drosophila)
    • Staufen RNA binding protein homolog 1
    • Staufen, RNA binding protein, homolog 1 (Drosophila)
    see all
  • 功能Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
  • 组织特异性Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
  • 序列相似性Contains 3 DRBM (double-stranded RNA-binding) domains.
  • 结构域One of the DRDB could be involved in RER binding.
    The C-terminal contains the tubulin binding domain (TBD).
  • 细胞定位Cytoplasm. Rough endoplasmic reticulum. Localizes exclusively with the rough reticulum endoplasmic.
  • Information by UniProt

Staufen peptide (ab110446)参考文献

ab110446 has not yet been referenced specifically in any publications.

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