Anti-Stathmin 1抗体(ab77271)


  • 产品名称Anti-Stathmin 1抗体
    参阅全部 Stathmin 1 一抗
  • 描述
    山羊多克隆抗体to Stathmin 1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Cow, Pig, Cynomolgus Monkey, Rhesus monkey
  • 免疫原

    Synthetic peptide:


    , corresponding to C terminal amino acids 135-149 of Human Stathmin 1 (NP_005554.1; NP_981944.1; NP_981946.1).

  • 阳性对照
    • Human testes lysate; mouse brain lysate.




Our Abpromise guarantee covers the use of ab77271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 17 kDa (predicted molecular weight: 17 kDa).
ELISA Use at an assay dependent dilution.


  • 功能Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear.
  • 组织特异性Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia.
  • 序列相似性Belongs to the stathmin family.
    Contains 1 SLD (stathmin-like) domain.
  • 翻译后修饰Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. MAPK is responsible for the phosphorylation of stathmin in response to NGF. Phosphorylation at Ser-16 seems to be required for neuron polarization (By similarity). Phosphorylation at Ser-63 reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity.
  • 细胞定位Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C1orf215 antibody
    • Lag antibody
    • LAP 18 antibody
    • LAP18 antibody
    • Leukemia associated phosphoprotein p18 antibody
    • Leukemia-associated phosphoprotein p18 antibody
    • Metablastin antibody
    • Oncoprotein 18 antibody
    • OP 18 antibody
    • Op18 antibody
    • p18 antibody
    • p19 antibody
    • Phosphoprotein 19 antibody
    • Phosphoprotein p19 antibody
    • pp17 antibody
    • pp19 antibody
    • PR22 antibody
    • Pr22 protein antibody
    • Prosolin antibody
    • Protein Pr22 antibody
    • SMN antibody
    • Stathmin antibody
    • Stathmin1 antibody
    • STMN 1 antibody
    • Stmn1 antibody
    • STMN1_HUMAN antibody
    see all

Anti-Stathmin 1 antibody 图像

  • Anti-Stathmin 1 antibody (ab77271) at 1 µg/ml + Human Testes Lysate (in RIPA buffer) at 35 µg

    Predicted band size : 17 kDa
    Observed band size : 17 kDa

Anti-Stathmin 1 antibody (ab77271)参考文献

ab77271 has not yet been referenced specifically in any publications.

Product Wall

I am sorry but I don't have specific information about the sensitivity or assay range.

Apologies for any inconvenience this may cause. If I can be of any further help, please just let me know.

Thank you for patience.

Here is further information about these products:

ab47468, ab47472, ab47464
Tested against the immunizing peptide in an indirect ELISA.

Solution Preparation:
Coating Solution:

Read More

Thank you for contacting us.

We have 4 antibodies suitable for human samples in ELISA. I have listed them below. I will try andobtain specific information about how they have been tested in ELISA.Could you confirm whether you have already te...

Read More