Anti-STAT5a (phospho S725) + STAT5b (phospho S730)抗体(ab194518)
Key features and details
- Rabbit polyclonal to STAT5a (phospho S725) + STAT5b (phospho S730)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-STAT5a (phospho S725) + STAT5b (phospho S730)抗体 -
描述
兔多克隆抗体to STAT5a (phospho S725) + STAT5b (phospho S730) -
宿主
Rabbit -
特异性
ab194518 detects endogenous levels of STAT5a + STAT5b only when phosphorylated at serine 725 / serine 730. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
This product was produced with the following immunogens:
Synthetic peptide corresponding to Human STAT5a (phospho S725) conjugated to keyhole limpet haemocyanin. (A-P-S(p)-P-V)
Database link: P42230
Synthetic peptide corresponding to Human STAT5b (phospho S730) conjugated to keyhole limpet haemocyanin. (A-P-S(p)-P-V)
Database link: P42232 -
阳性对照
- EGF treated Jurkat cell extracts.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.87% Sodium chloride
PBS without Mg2+ and Ca2+. -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab194518 was purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab194518于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 91, 90 kDa.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 91, 90 kDa. |
靶标
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细胞定位
STAT5a: Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation. STAT5b: Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation. -
数据库链接
- Entrez Gene: 6776 Human
- Entrez Gene: 6777 Human
- Omim: 601511 Human
- Omim: 604260 Human
- SwissProt: P42229 Human
- SwissProt: P51692 Human
- Unigene: 437058 Human
- Unigene: 595276 Human
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab194518 被引用在 1 文献中.
- You YH et al. MicroRNA-153 promotes brain-derived neurotrophic factor and hippocampal neuron proliferation to alleviate autism symptoms through inhibition of JAK-STAT pathway by LEPR. Biosci Rep 39:N/A (2019). PubMed: 30975733