Anti-STAT5a抗体,prediluted (ab15525)

概述

  • 产品名称
    Anti-STAT5a抗体,prediluted
    参阅全部 STAT5a 一抗
  • 描述
    兔多克隆抗体to STAT5a,prediluted
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Rabbit) (C terminal).

  • 阳性对照
    • A431 cells and tonsil.

性能

应用

Our Abpromise guarantee covers the use of ab15525 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/200. Predicted molecular weight: 91 kDa.
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 功能
    Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
  • 序列相似性
    Belongs to the transcription factor STAT family.
    Contains 1 SH2 domain.
  • 翻译后修饰
    Tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity.
  • 细胞定位
    Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Mammary gland factor antibody
    • MGF antibody
    • Signal transducer and activator of transcription 5A antibody
    • STA5A_HUMAN antibody
    • STAT 5 antibody
    • STAT 5A antibody
    • STAT5 antibody
    • STAT5A antibody
    see all

图片

  • ab15525 staining STAT5a in human breast carcinoma by Immunocytochemistry (FFPE-sections).
  • Anti-STAT5a antibody, prediluted (ab15525) at 1/25 dilution + K562 cell lysate

    Predicted band size: 91 kDa
    Observed band size: 91 kDa

文献

ab15525 has not yet been referenced specifically in any publications.

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