概述

  • 产品名称Anti-STAT5a抗体
    参阅全部 STAT5a 一抗
  • 描述
    兔多克隆抗体to STAT5a
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Three synthetic peptides (Human) conjugated to KLH

  • 阳性对照
    • An induced culture of E. coli

性能

应用

Our Abpromise guarantee covers the use of ab86030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/1000. Detects a band of approximately 105 kDa (predicted molecular weight: 91 kDa). Tag is 14kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
    • 序列相似性Belongs to the transcription factor STAT family.
      Contains 1 SH2 domain.
    • 翻译后修饰Tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity.
    • 细胞定位Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Mammary gland factor antibody
      • MGF antibody
      • Signal transducer and activator of transcription 5A antibody
      • STA5A_HUMAN antibody
      • STAT 5 antibody
      • STAT 5A antibody
      • STAT5 antibody
      • STAT5A antibody
      see all

    Anti-STAT5a antibody 图像

    • All lanes : Anti-STAT5a antibody (ab86030) at 1/1000 dilution

      Lane 1 : An un-induced culture of E. coli
      Lane 2 : An induced culture of E. coli

      Lysates/proteins at 1/5000 dilution per lane.

      Secondary
      Anti-Rabbit IgG HRP at 1/1000 dilution

      Predicted band size : 91 kDa
      Observed band size : 49,75,105 kDa (why is the actual band size different from the predicted?)


      Exposure time : 60 minutes

    Anti-STAT5a antibody (ab86030)参考文献

    ab86030 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"