概述

  • 产品名称Anti-STAT4抗体
    参阅全部 STAT4 一抗
  • 描述
    兔多克隆抗体to STAT4
  • 特异性Detects endogenous levels of total STAT4 protein.
  • 经测试应用适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic non-phosphopeptide derived from human STAT4 around the phosphorylation site of Tyrosine 693 (KGYVP)

  • 阳性对照
    • Extracts from RAW264.7 cells treated with EGF (200 ng/ml for 5 mins); human breast carcinoma tissue

性能

应用

Our Abpromise guarantee covers the use of ab55357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/40000.
WB 1/500 - 1/1000. Detects a band of approximately 86 kDa (predicted molecular weight: 86 kDa).
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
  • 疾病相关Systemic lupus erythematosus 11
    Rheumatoid arthritis
  • 序列相似性Belongs to the transcription factor STAT family.
    Contains 1 SH2 domain.
  • 翻译后修饰Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity.
  • 细胞定位Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Signal transducer and activator of transcription 4 antibody
    • SLEB11 antibody
    • STAT4 antibody
    • STAT4_HUMAN antibody

Anti-STAT4 antibody 图像

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab55357 at 1/50 dilution. Left: without immunizing peptide; Right: with immunizing peptide
  • All lanes : Anti-STAT4 antibody (ab55357) at 1/500 dilution

    Lane 1 : extracts from RAW264.7 cells treated with EGF (200 ng/ml for 5 mins) with immunizing peptide
    Lane 2 : extracts from RAW264.7 cells treated with EGF (200 ng/ml for 5 mins)


    Predicted band size : 86 kDa
    Observed band size : 86 kDa

Anti-STAT4 antibody (ab55357)参考文献

ab55357 has not yet been referenced specifically in any publications.

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