概述

  • 产品名称Anti-STAT4抗体
    参阅全部 STAT4 一抗
  • 描述
    山羊多克隆抗体to STAT4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog, Pig
  • 免疫原

    Synthetic peptide:

    DHSESGEVRFHSVEP

    by a Cysteine residue linker, corresponding to internal sequence amino acids 613-627 of Human STAT4 (NP_003142.1)

  • 阳性对照
    • Transfected HEK293 transiently expressing full-length Human STAT4

性能

应用

Our Abpromise guarantee covers the use of ab105029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 0.5 µg/ml. Predicted molecular weight: 86 kDa.

靶标

  • 功能Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
  • 疾病相关Systemic lupus erythematosus 11
    Rheumatoid arthritis
  • 序列相似性Belongs to the transcription factor STAT family.
    Contains 1 SH2 domain.
  • 翻译后修饰Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity.
  • 细胞定位Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Signal transducer and activator of transcription 4 antibody
    • SLEB11 antibody
    • STAT4 antibody
    • STAT4_HUMAN antibody

Anti-STAT4 antibody 图像

  • Lanes 1 - 2 : Anti-STAT4 antibody (ab105029) at 1 µg/ml
    Lane 3 : Anti-myc antibody at 1/1000 dilution

    Lane 1 : HEK293 lysate overexpressing Human STAT4 with C-terminal MYC tag
    Lane 2 : Mock-transfected HEK293
    Lane 3 : HEK293 lysate overexpressing human STAT4 with C-terminal MYC tag


    Predicted band size : 86 kDa

Anti-STAT4 antibody (ab105029)参考文献

ab105029 has not yet been referenced specifically in any publications.

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