1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
功能Catalyzes the formation of ganglioside GM3 (alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide).
组织特异性Ubiquitous. High expression in brain, skeletal muscle, placenta, and testis.
疾病相关Defects in ST3GAL5 are the cause of Amish infantile epilepsy syndrome (AIES) [MIM:609056]. AIES is an autosomal recessive, infantile-onset symptomatic epilepsy associated with developmental stagnation and blindness.
序列相似性Belongs to the glycosyltransferase 29 family.
Immunohistochemistry analysis in formalin fixed and paraffin embedded Human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. ab107534 at a dilution of 1/50.
Anti-ST3GAL5 antibody (ab107534)参考文献
has not yet been referenced specifically in any publications.