概述

  • 产品名称Anti-ST2抗体
    参阅全部 ST2 一抗
  • 描述
    兔多克隆抗体to ST2
  • 特异性ab72778 is specific to Isoform C of ST2
  • 经测试应用适用于: Flow Cyt, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to a region between residues 200-250 of human ST2 protein

  • 阳性对照
    • Daudi and NIH3T3 cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab72778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. PubMed: 24388011ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
WB Use a concentration of 3 - 5 µg/ml. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).

靶标

  • 功能Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.
  • 组织特异性Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.
  • 序列相似性Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DER-4 antibody
    • DER4 antibody
    • FIT 1 antibody
    • Growth stimulation expressed antibody
    • homolog of mouse growth stimulation-expressed antibody
    • Il1rl1 antibody
    • IL33R antibody
    • ILRL1_HUMAN antibody
    • Interleukin 1 receptor like 1 antibody
    • interleukin 1 receptor related protein antibody
    • Interleukin-1 receptor-like 1 antibody
    • Protein ST2 antibody
    • ST2 antibody
    • ST2L antibody
    • ST2V antibody
    • T1 antibody
    • T1 protein antibody
    see all

Anti-ST2 antibody 图像

  • Lanes 1 - 2 : Anti-ST2 antibody (ab72778) at 5 µg/ml
    Lane 3 : Anti-ST2 antibody (ab72778) at 3 µg/ml

    Lane 1 : Daudi cell lysate
    Lane 2 : Daudi cell lysate with immunizing peptide
    Lane 3 : NIH3T3 cell lysate


    Predicted band size : 29 kDa
    Observed band size : 29 kDa

Anti-ST2 antibody (ab72778)参考文献

This product has been referenced in:
  • Xue L  et al. Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. J Allergy Clin Immunol 133:1184-94 (2014). Flow Cyt ; Human . Read more (PubMed: 24388011) »

See 1 Publication for this product

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