The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 24388011ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
Use a concentration of 3 - 5 µg/ml. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).
功能Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.
组织特异性Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.
序列相似性Belongs to the interleukin-1 receptor family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 TIR domain.
homolog of mouse growth stimulation-expressed antibody
Interleukin 1 receptor like 1 antibody
interleukin 1 receptor related protein antibody
Interleukin-1 receptor-like 1 antibody
Protein ST2 antibody
T1 protein antibody
Anti-ST2 antibody 图像
Western blot - ST2 antibody (ab72778)
Lanes 1 - 2 : Anti-ST2 antibody (ab72778) at 5 µg/ml Lane 3 : Anti-ST2 antibody (ab72778) at 3 µg/ml
Lane 1 : Daudi cell lysate Lane 2 : Daudi cell lysate with immunizing peptide Lane 3 : NIH3T3 cell lysate
Predicted band size : 29 kDa Observed band size : 29 kDa
Anti-ST2 antibody (ab72778)参考文献
This product has been referenced in:
Xue L et al. Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. J Allergy Clin Immunol133:1184-94 (2014).
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