Anti-ST14抗体- Catalytic domain (ab28266)


  • 产品名称
    Anti-ST14抗体- Catalytic domain
    参阅全部 ST14 一抗
  • 描述
    兔多克隆抗体to ST14 - Catalytic domain
  • 宿主
  • 特异性
    This antibody does not recognize matriptase 2 (MTSP2).
  • 经测试应用
    适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide based on the catalytic domain of Human ST14.

    (Peptide available as ab41264.)



Our Abpromise guarantee covers the use of ab28266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 µg/ml.
WB Use at an assay dependent dilution. Predicted molecular weight: 95 kDa. A recommended starting concentration for Western blots is 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates.


  • 功能
    Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
  • 疾病相关
    Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH) [MIM:610765]. ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.
  • 序列相似性
    Belongs to the peptidase S1 family.
    Contains 2 CUB domains.
    Contains 4 LDL-receptor class A domains.
    Contains 1 peptidase S1 domain.
  • 细胞定位
  • Information by UniProt
  • 数据库链接
  • 别名
    • Epithin antibody
    • HAI antibody
    • Matriptase antibody
    • Membrane type serine protease 1 antibody
    • Membrane type serine protease antibody
    • Membrane-type serine protease 1 antibody
    • MT SP1 antibody
    • MT-SP1 antibody
    • MTSP 1 antibody
    • MTSP1 antibody
    • Prostamin antibody
    • PRSS 14 antibody
    • PRSS14 antibody
    • Serine protease 14 antibody
    • Serine protease TADG 15 antibody
    • Serine protease TADG-15 antibody
    • Serine protease TADG15 antibody
    • SNC 19 antibody
    • SNC19 antibody
    • ST 14 antibody
    • ST14 antibody
    • ST14_HUMAN antibody
    • Suppression of tumorigenicity 14 (colon carcinoma matriptase epithin) antibody
    • Suppression of tumorigenicity 14 (colon carcinoma) antibody
    • Suppression of tumorigenicity 14 antibody
    • Suppressor of tumorigenicity 14 protein antibody
    • Suppressor of tumorigenicity protein 14 antibody
    • TADG 15 antibody
    • TADG15 antibody
    • TMPRSS14 antibody
    • Tumor associated differentially expressed gene 15 protein antibody
    • Tumor-associated differentially-expressed gene 15 protein antibody
    see all


  • ICC/IF image of ab28266 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab28266, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.


This product has been referenced in:
  • Sun P  et al. Regulation of matriptase and HAI-1 system, a novel therapeutic target in human endometrial cancer cells. Oncotarget 9:12682-12694 (2018). Read more (PubMed: 29560101) »
  • Sun P  et al. Decreasing the ratio of matriptase/HAI-1 by downregulation of matriptase as a potential adjuvant therapy in ovarian cancer. Mol Med Rep 14:1465-74 (2016). WB ; Human . Read more (PubMed: 27356668) »

See all 2 Publications for this product


Thank you for contacting us. After having discussion with my lab colleagues, regrettably I have to say we have not tested the cross reactivity of these antibodies with Matriptase 2. We do not have any data for sharing. The matriptase 2 non reac...

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