概述

  • 产品名称Anti-SSX2IP抗体
    参阅全部 SSX2IP 一抗
  • 描述
    兔多克隆抗体to SSX2IP
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 564-614 of Human SSX2IP (NP_001159765.1).

  • 阳性对照
    • 293T, Jurkat and HeLa cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab117754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 71 kDa.
IP Use at 2-10 µg/mg of lysate.

靶标

  • 功能Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin.
  • 组织特异性Widely expressed, with the highest expression in brain, intermediate expression in kidney, testis, spinal cord, liver, heart, lung, skeletal muscle, ovary, fetal liver and fetal brain, and little to no expression in pancreas and spleen. All specific brain regions showed intermediate to high expression, with highest expression in amygdala. Also expressed in fetal tissues, mainly in liver and brain.
  • 结构域Both the N-terminal (up to position 79) and the C-terminal (from position 304) sequences are required for interaction with SSX2.
  • 细胞定位Cell junction > adherens junction. Nucleus. Not found at cell-matrix AJs.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ADIP antibody
    • ADIP_HUMAN antibody
    • Afadin and alpha actinin binding protein antibody
    • Afadin DIL domain interacting protein antibody
    • Afadin DIL domain-interacting protein antibody
    • Afadin- and alpha-actinin-binding protein antibody
    • FLJ10848 antibody
    • KIAA0923 antibody
    • MGC75026 antibody
    • OTTHUMP00000011574 antibody
    • SSX 2 interacting protein antibody
    • SSX2 interacting protein antibody
    • SSX2-interacting protein antibody
    • SSX2IP antibody
    • Synovial sarcoma X breakpoint 2 interacting protein antibody
    see all

Anti-SSX2IP antibody 图像

  • Detection of SSX2IP by Western Blot of Immunprecipitate.
    ab117754 at 1µg/ml staining SSX2IP in 293T whole cell lysate immunoprecipitated using ab117754 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 30 seconds.
  • All lanes : Anti-SSX2IP antibody (ab117754) at 0.4 µg/ml

    Lane 1 : 293T cell line lysate at 50 µg
    Lane 2 : 293T cell line lysate at 15 µg
    Lane 3 : Jurkat cell line lysate at 50 µg
    Lane 4 : HeLa cell line lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 71 kDa


    Exposure time : 3 minutes

Anti-SSX2IP antibody (ab117754)参考文献

ab117754 has not yet been referenced specifically in any publications.

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