Anti-SSX1抗体[1E10] (ab119036)

概述

  • 产品名称Anti-SSX1抗体[1E10]
    参阅全部 SSX1 一抗
  • 描述
    小鼠单克隆抗体[1E10] to SSX1
  • 经测试应用适用于: WB, Flow Cyt, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length Human SSX1 produced in E.coli (NP_005626).

  • 阳性对照
    • HEK293T cell lysate transfected with pCMV6-ENTRY SSX1 cDNA; COS7 cells transiently transfected with pCMV6-ENTRY SSX1; HEK293T cells transfected with a SSX1 overexpress plasmid; Hela cells; Jurkat cells
  • 常规说明Dilute in PBS (pH7.3) before use.

性能

应用

Our Abpromise guarantee covers the use of ab119036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 22 kDa.
Flow Cyt 1/100. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ICC/IF 1/100.

靶标

  • 功能Could act as a modulator of transcription.
  • 组织特异性Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
  • 疾病相关Note=A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • 序列相似性Belongs to the SSX family.
    Contains 1 KRAB-related domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cancer/testis antigen 5.1 antibody
    • Cancer/testis antigen family 5 member 1 antibody
    • CT5.1 antibody
    • MGC150425 antibody
    • MGC5162 antibody
    • Protein SSX1 antibody
    • sarcoma, synovial, X chromosome related 1 antibody
    • SSRC antibody
    • SSX1 antibody
    • SSX1_HUMAN antibody
    • Synovial sarcoma antibody
    • Synovial sarcoma, X breakpoint 1 antibody
    • X breakpoint 1 antibody
    see all

Anti-SSX1 antibody [1E10] 图像

  • All lanes : Anti-SSX1 antibody [1E10] (ab119036) at 1/500 dilution

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY SSX1 cDNA

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 22 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC201600)
  • ab119036, at 1/100 dilution, staining SSX1 in COS7 cells transiently transfected with pCMV6-ENTRY SSX1 by Immunofluorescence.
  • HEK293T cells transfected with either a SSX1 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained using ab119036 at 1/100 dilution and then analyzed by flow cytometry.
  • Flow cytometric analysis of SSX1 in Hela cells, using ab119036 at 1/100 dilution (Red) compared to a nonspecific negative control antibody (Blue).
  • Flow cytometric analysis of SSX1 in Jurkat cells using ab119036 at 1/100 dilution (Red) compared to a nonspecific negative control antibody (Blue).

Anti-SSX1 antibody [1E10] (ab119036)参考文献

ab119036 has not yet been referenced specifically in any publications.

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