Anti-SRRM4抗体(ab112092)

概述

  • 产品名称Anti-SRRM4抗体
  • 描述
    兔多克隆抗体to SRRM4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 270-319 (KTASPLTTSR GRSQEYDSGN DTSSPPSTQT SSARSRGQEK GSPSGGLSKS) of Human SRRM4 (NP_919262).

  • 阳性对照
    • Human Fetal Liver lysate.

性能

应用

Our Abpromise guarantee covers the use of ab112092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 69 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts.
  • 组织特异性Specifically expressed in neuronal cells (at protein level). Expressed in the cerebellum.
  • 序列相似性Belongs to the nSR100 family.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1500001A10Rik antibody
    • B230202K19Rik antibody
    • KIAA1853 antibody
    • Medulloblastoma antigen MU-MB-2.76 antibody
    • mKIAA1853 antibody
    • Neural-specific serine/arginine repetitive splicing factor of 100 kDa antibody
    • Neural-specific SR-related protein of 100 kDa antibody
    • nSR100 antibody
    • RGD1560213 antibody
    • Serine/arginine repetitive matrix protein 4 antibody
    • Srrm4 antibody
    • SRRM4_HUMAN antibody
    see all

Anti-SRRM4 antibody 图像

  • Anti-SRRM4 antibody (ab112092) at 1 µg/ml + Human Fetal Liver lysate at 10 µg

    Predicted band size : 69 kDa

Anti-SRRM4 antibody (ab112092)参考文献

ab112092 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam.

I have talked to the lab about your questions and please find their response below:

Based on the reviewed UniProt entry for this gene (http://www.uniprot.org/uniprot/A7MD48), it is predicted to have a M...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"