概述

  • 产品名称
    Anti-SRPR beta抗体
    参阅全部 SRPR beta 一抗
  • 描述
    羊多克隆抗体to SRPR beta
  • 经测试应用
    适用于: WB, IPmore details
  • 种属反应性
    与反应: Dog
  • 免疫原

    Synthetic peptide, corresponding to C terminal amino acids 246-265 of Dog SRPR beta.

  • 阳性对照
    • Canine microsomal protein.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.08% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯化说明
    Purified by ammonium sulfate precipitation This antibody is provided as a 0.2 µm sterile filtered solution.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab16146 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 30 kDa.
IP Use at an assay dependent dilution.

靶标

  • 功能
    Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.
  • 序列相似性
    Belongs to the SRP receptor beta subunit family.
  • 细胞定位
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • 别名
    • APMCF1 antibody
    • Protein APMCF1 antibody
    • Signal recognition particle receptor B subunit antibody
    • Signal recognition particle receptor beta subunit antibody
    • Signal recognition particle receptor subunit beta antibody
    • SR-beta antibody
    • SRbeta antibody
    • SRPR beta antibody
    • Srprb antibody
    • SRPRB_HUMAN antibody
    see all

图片

  • ab16146 detecting SRPR beta from canine microsomal protein by western blot Lane 1: 3ng of canine microsomal protein Lane 2: 6ng of canine microsomal protein Lane 3: 12ng of canine microsoaml protein

文献

This product has been referenced in:
  • Lakkaraju AK  et al. Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation. Mol Biol Cell 23:2712-22 (2012). WB . Read more (PubMed: 22648169) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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