概述

  • 产品名称Anti-SRPK1抗体
    参阅全部 SRPK1 一抗
  • 描述
    小鼠单克隆抗体to SRPK1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: NETLRHKEDL HNANDCDVQN LNQESSFLSS QNGDSSTSQE TDSCTPITSE VSDTMVCQSS STVGQSFSEQ HISQLQESIR AEIPCEDEQE QEHNGPLDNK , corresponding to amino acids 371-470 of Human SRPK1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab58003 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.
    • 组织特异性Isoform 2 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 is only seen in the testis, at lower levels than isoform 2.
    • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
      Contains 1 protein kinase domain.
    • 细胞定位Cytoplasm. Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Serine/arginine rich protein specific kinase 1 antibody
      • Serine/arginine rich splicing factor kinase 1 antibody
      • Serine/arginine-rich protein-specific kinase 1 antibody
      • Serine/threonine protein kinase SRPK1 antibody
      • Serine/threonine-protein kinase SRPK1 antibody
      • SFRS protein kinase 1 antibody
      • SFRSK1 antibody
      • SR protein kinase 1 antibody
      • SR protein specific kinase 1 antibody
      • SR-protein-specific kinase 1 antibody
      • SRPK1 antibody
      • SRPK1_HUMAN antibody
      see all

    Anti-SRPK1 antibody 图像



    • Predicted band size : 92 kDa
      SRPK1 antibody (ab58003) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-SRPK1 antibody (ab58003)参考文献

    ab58003 has not yet been referenced specifically in any publications.

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