Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
Bone marrow failure, familial
Belongs to the SRP72 family. Contains 5 TPR repeats.
The C-terminus is essential for the interaction with the SRP68/7S RNA complex.