概述

  • 产品名称Anti-SRA1抗体
    参阅全部 SRA1 一抗
  • 描述
    兔多克隆抗体to SRA1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Guinea pig, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 92-141 (SGPASGVEPT SFPVESEAVM EDVLRPLEQA LEDCRGHTRK QVCDDISRRL) of Human SRA1 (NP_001030312).

  • 阳性对照
    • HT1080 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab118676 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
  • 组织特异性Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up-regulated in human tumors of the breast, ovary, and uterus.
  • 序列相似性Belongs to the SRA1 family.
  • 细胞定位Nucleus. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC87674 antibody
    • PP7684 antibody
    • SR A1 antibody
    • SRA antibody
    • SRA1 antibody
    • SRA1_HUMAN antibody
    • SRAP antibody
    • Steroid receptor coactivator antibody
    • Steroid receptor RNA activator 1 (complexes with NCOA1) antibody
    • Steroid receptor RNA activator 1 antibody
    • Steroid receptor RNA activator protein antibody
    • STRAA1 antibody
    see all

Anti-SRA1 antibody 图像

  • Anti-SRA1 antibody (ab118676) at 1 µg/ml + HT1080 cell lysate at 10 µg

    Predicted band size : 26 kDa

Anti-SRA1 antibody (ab118676)参考文献

ab118676 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"