概述

  • 产品名称Anti-SPTBN1抗体
    参阅全部 SPTBN1 一抗
  • 描述
    兔多克隆抗体to SPTBN1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region between residues 2150 and 2200 of Human SPTBN1 (NP_003119.2).

  • 阳性对照
    • Human prostate adenocarcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab84498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
    • 组织特异性Isoform 2 is present in brain, lung and kidney (at protein level).
    • 序列相似性Belongs to the spectrin family.
      Contains 2 CH (calponin-homology) domains.
      Contains 1 PH domain.
      Contains 17 spectrin repeats.
    • 翻译后修饰Isoform 2 is phosphorylated on Ser-8 and Ser-10.
    • 细胞定位Cell membrane and Cytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > M line. Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Beta G spectrin antibody
      • Beta II spectrin antibody
      • Beta spectrin 2 antibody
      • Beta spectrin II antibody
      • Beta-II spectrin antibody
      • betaSpII antibody
      • brain 1 antibody
      • ELF antibody
      • Embryonic liver beta fodrin antibody
      • Fodrin beta chain antibody
      • non-erythroid beta chain 1 antibody
      • Spectrin antibody
      • Spectrin beta chain antibody
      • Spectrin, beta, non erythrocytic 1 antibody
      • Spectrin, non erythroid beta chain 1 antibody
      • SPTB2 antibody
      • SPTB2_HUMAN antibody
      • SPTBN1 antibody
      see all

    Anti-SPTBN1 antibody 图像

    • ab84498, at 1/250 dilution, staining SPTBN1 in formalin-fixed, paraffin-embedded human prostate adenocarcinoma by Immunohistochemistry, using DAB staining.

    Anti-SPTBN1 antibody (ab84498)参考文献

    ab84498 has not yet been referenced specifically in any publications.

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