概述

  • 产品名称Anti-SPRR1b抗体
    参阅全部 SPRR1b 一抗
  • 描述
    兔多克隆抗体to SPRR1b
  • 经测试应用适用于: IHC-Fr, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Cow, Cat, Pig
  • 免疫原

    Synthetic peptide corresponding to amino acids 48-89 (PCHPKVPEPCHPKVPEPCQPKVPEPCHPKVPEPCPSIVTPAPAQQKTKQ K) of human SPRR1b (NP_003116).

  • 阳性对照
    • Jurkat cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG

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应用

Our Abpromise guarantee covers the use of ab123237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/50.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 10 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
  • 组织特异性Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.
  • 序列相似性Belongs to the cornifin (SPRR) family.
  • 发展阶段Expressed during differentiation of squamous cells.
  • 翻译后修饰The N-terminus is blocked.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 14.9 kDa pancornulin antibody
    • Cornifin antibody
    • Cornifin B antibody
    • Cornifin-B antibody
    • CornifinB antibody
    • GADD33 antibody
    • MGC61901 antibody
    • Small proline rich protein IB antibody
    • Small proline-rich protein IB antibody
    • SPR-IB antibody
    • SPR1B_HUMAN antibody
    • SPRIB antibody
    • SPRR1 antibody
    • SPRR1B antibody
    see all

Anti-SPRR1b antibody 图像

  • Immunohistochemistry (Frozen sections) analysis of mouse eyeball sections labelling  SPRR1b with ab123237 at 1:50. An Alexa Fluor 488-conjugated goat anti-rabbit IgG (1:50) was used as the secondary antibody.

  • Anti-SPRR1b antibody (ab123237) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG HRP

    Predicted band size : 10 kDa
    Gel concentration: 10-20%.

Anti-SPRR1b antibody (ab123237)参考文献

This product has been referenced in:
  • Fang Z  et al. Long non-coding RNA MALAT-1 modulates metastatic potential of tongue squamous cell carcinomas partially through the regulation of small proline rich proteins. BMC Cancer 16:706 (2016). WB ; Human . Read more (PubMed: 27586393) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"