Anti-Sprouty 1抗体[3H4] (ab117744)

概述

  • 产品名称Anti-Sprouty 1抗体[3H4]
    参阅全部 Sprouty 1 一抗
  • 描述
    小鼠单克隆抗体[3H4] to Sprouty 1
  • 经测试应用适用于: WB, IHC-P, Sandwich ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein of Human Sprouty 1 (AAC39566.1).

  • 阳性对照
    • HepG2 cell lysate and Sprouty 1 transfected 293T cell lysate; Human Heart tissue, recombinant Human Sprouty 1 protein.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液pH: 7.40
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Ascites
  • 克隆单克隆
  • 克隆编号3H4
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab117744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 35 kDa.
IHC-P Use a concentration of 5 µg/ml.
Sandwich ELISA Use at an assay dependent concentration.

靶标

  • 功能May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
  • 序列相似性Belongs to the sprouty family.
    Contains 1 SPR (sprouty) domain.
  • 结构域The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.
  • 细胞定位Cytoplasm. Membrane. Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hSPRY1 antibody
    • Protein sprouty homolog 1 antibody
    • Sprouty homolog 1 antagonist of FGF signaling antibody
    • Sprouty homolog 1 antibody
    • Spry-1 antibody
    • Spry1 antibody
    • SPY1_HUMAN antibody
    see all

Anti-Sprouty 1 antibody [3H4] 图像

  • Anti-Sprouty 1 antibody [3H4] (ab117744) + HepG2 cell lysate

    Predicted band size : 35 kDa
  • All lanes : Anti-Sprouty 1 antibody [3H4] (ab117744)

    Lane 1 : 293T cell lysate, transfected with Sprouty 1
    Lane 2 : 293T cell lysate, non-transfected


    Predicted band size : 35 kDa
  • ab117744, at 5 µg/ml, staining Sprouty 1 in Formalin-fixed, Paraffin-embedded Human Heart tissue by Immunohistochemistry.
  • Detection limit for recombinant tagged Sprouty 1 is approximately 0.03ng/ml (ab117744) as a capture antibody.

Anti-Sprouty 1 antibody [3H4] (ab117744)参考文献

ab117744 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"