概述

  • 产品名称Anti-SPINK9抗体
  • 描述
    兔多克隆抗体to SPINK9
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: KQMVDCSHYK KLPPGQQRFC HHMYDPICGS DGKTYKNDCF FCSKVKKTDG TLKFVH, corresponding to amino acids 27-82 of Human SPINK9.

  • 阳性对照
    • Human liver tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab122454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

靶标

  • 功能Serine protease inhibitor which specifically inhibits KLK5. May contribute to the regulation of the desquamation process in skin by inhibiting KLK5.
  • 组织特异性Skin. Highly expressed at sites of hyperkeratosis. Also detected in thymus, tonsils, testis, pancreas, liver, placenta and brain. Expressed at stratum granulosum and stratum corneum at palmar and plantar sites (at protein level).
  • 序列相似性Contains 1 Kazal-like domain.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ISK9_HUMAN antibody
    • LEKTI2 antibody
    • Lymphoepithelial Kazal-type-related inhibitor 2 antibody
    • Serine protease inhibitor Kazal-type 9 antibody
    • SPINK9 antibody
    see all

Anti-SPINK9 antibody 图像

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli. Recommended concentration of ab122454 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122454, at 1/20 dilution, staining SPINK9 in paraffin embedded Human liver tissue by Immunohistochemistry.

Anti-SPINK9 antibody (ab122454)参考文献

ab122454 has not yet been referenced specifically in any publications.

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