This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Anti-Spindle E抗体(ab5204)

概述

  • 产品名称Anti-Spindle E抗体
  • 描述
    兔多克隆抗体to Spindle E

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • 种属反应性

    预测可用于: Drosophila melanogaster
  • 免疫原

    Synthetic peptide derived from residues 1400 to the C terminus of Drosophila melanogaster Spindle E.

    .

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

  • 应用说明Tested in peptide ELISA.
    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Spindle-E or spn-E encodes a putative DEAD-box helicase, spn-E, which has been shown to be required for RNAi in Drosophila oocytes. Mutations in the aubergine and spindle-E genes, members of the Argonaute and RNA helicase gene families, respectively, impair silencing by eliminating the short Su(Ste) RNA, but have no effect on microRNA production Mutations in Piwi, Aubergine, or Spindle-E, which encode RNAi components result in reduction of H3 Lys9 methylation and delocalization of HP1 and HP2. RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine (the Argonaute protein) and spindle-E.
    • 细胞定位Nuclear
    • 数据库链接
      • 别名
        • CG3158 antibody
        • CG3158 PA antibody
        • female sterile(3)homeless antibody
        • Fs(1)hls antibody
        • Hls antibody
        • homeless antibody
        • Spindle E CG3158 PA antibody
        • SpindleE antibody
        • Spn E antibody
        • Spn E/hls antibody
        • SpnE antibody
        see all

      Anti-Spindle E antibody (ab5204)参考文献

      ab5204 has not yet been referenced specifically in any publications.

      Product Wall

      Thank you for your enquiry. Spindle-E is part of the RNA interference machinery and therefore a nuclear protein. You may wish to consult the reference: Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machi...

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"