概述

  • 产品名称
  • 描述
    兔多克隆抗体to Spic
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish, Spider monkey
  • 免疫原

    Synthetic peptide corresponding to a region within the C-terminal amino acids 148-197 (EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI) of Human Spic (NP_689536.1).

  • 阳性对照
    • Human Renal ACHN Cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab118953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 29 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
  • 组织特异性
    Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
  • 序列相似性
    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AU019198 antibody
    • C76795 antibody
    • MGC40611 antibody
    • MGC80555 antibody
    • Prf antibody
    • Pu.1 related factor antibody
    • Spi C antibody
    • Spi C transcription factor antibody
    • Spi-C transcription factor (Spi-1/PU.1 related) antibody
    • spiC antibody
    • SPIC_HUMAN antibody
    • Transcription factor Spi-C antibody
    see all

图片

  • Anti-Spic antibody (ab118953) at 1 µg/ml + ACHN Cell lysate at 10 µg

    Predicted band size : 29 kDa

实验方案

文献

ab118953 has not yet been referenced specifically in any publications.

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