概述

  • 产品名称
  • 描述
    兔多克隆抗体to SPHK1
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human SPHK1 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • 阳性对照
    • Adrenal tissue (pheochromocytes).

性能

应用

Our Abpromise guarantee covers the use of ab61148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能
    Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
  • 组织特异性
    Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle.
  • 序列相似性
    Contains 1 DAGKc domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • SK 1 antibody
    • SK1 antibody
    • Sphingosine kinase 1 antibody
    • SPHK 1 antibody
    • SPHK antibody
    • Sphk1 antibody
    • SPHK1_HUMAN antibody
    • SPK antibody
    • SPK 1 antibody
    see all

图片

  • Ab61148 (10ug/ml) staining human SPHK1 in human adrenal tissue (pheochromocytes) by immunohistochemistry using formalin fixed, paraffin embedded tissue.

文献

ab61148 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab61148.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册