概述

  • 产品名称Anti-SPHK1抗体
    参阅全部 SPHK1 一抗
  • 描述
    小鼠单克隆抗体to SPHK1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-385 of Human SPHK1

性能

应用

Our Abpromise guarantee covers the use of ab56414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
    • 组织特异性Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle.
    • 序列相似性Contains 1 DAGKc domain.
    • Information by UniProt
    • 数据库链接
    • 别名
      • SK 1 antibody
      • SK1 antibody
      • Sphingosine kinase 1 antibody
      • SPHK 1 antibody
      • SPHK antibody
      • Sphk1 antibody
      • SPHK1_HUMAN antibody
      • SPK antibody
      • SPK 1 antibody
      see all

    Anti-SPHK1 antibody 图像



    • Predicted band size : 43 kDa
      SPHK1 antibody (ab56414) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    Anti-SPHK1 antibody (ab56414)参考文献

    This product has been referenced in:
    • Gellings Lowe N  et al. Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts. Cardiovasc Res 82:303-12 (2009). Read more (PubMed: 19228708) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"