概述

  • 产品名称Anti-Sphingomyelin Synthase 1抗体
    参阅全部 Sphingomyelin Synthase 1 一抗
  • 描述
    兔多克隆抗体to Sphingomyelin Synthase 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    A synthetic peptide corresponding to a region within internal amino acids 144 - 193 (SCFVLTTVMI SVVHERVPPK EVQPPLPDTF FDHFNRVQWA FSICEINGMI) of Human Sphingomyelin Synthase 1 (NP_671512)

  • 阳性对照
    • HeLa cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab83856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性Sphingomyelin synthase 1 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Sphingomyelin synthase 1 is required for cell growth and is also capable of suppressing BAX-mediated apoptosis and preventing cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. It may protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
  • 细胞定位Golgi Apparatus. Multi-pass membrane protein
  • 数据库链接
  • 别名
    • MOB antibody
    • Phosphatidylcholine:ceramide cholinephosphotransferase 1 antibody
    • Protein Mob antibody
    • SGMS1 antibody
    • SMS 1 antibody
    • SMS1 antibody
    • TMEM23 antibody
    • Transmembrane protein 23 antibody
    see all

Anti-Sphingomyelin Synthase 1 antibody 图像

  • Anti-Sphingomyelin Synthase 1 antibody (ab83856) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 49 kDa
    Observed band size : 49 kDa

Anti-Sphingomyelin Synthase 1 antibody (ab83856)参考文献

This product has been referenced in:
  • Yachi R  et al. Subcellular localization of sphingomyelin revealed by two toxin-based probes in mammalian cells. Genes Cells 17:720-7 (2012). WB ; African Green Monkey . Read more (PubMed: 22747662) »

See 1 Publication for this product

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