Anti-Spermine synthase抗体(ab101458)

概述

  • 产品名称Anti-Spermine synthase抗体
    参阅全部 Spermine synthase 一抗
  • 描述
    兔多克隆抗体to Spermine synthase
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment corresponding to a region within amino acids 144-336 of Human Spermine synthase (AAH09898).

  • 阳性对照
    • 293T, A431 and Jurkat whole cell lysates; Raji cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab101458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 41 kDa.

靶标

  • 功能Required for normal viability, growth and fertility.
  • 通路Amine and polyamine biosynthesis; spermine biosynthesis; spermine from spermidine: step 1/1.
  • 疾病相关Defects in SMS are the cause of Snyder-Robinson syndrome (SRS) [MIM:309583]; also known as X-linked mental retardation Snyder-Robinson type. SRS is characterized by moderate intellectual deficit, hypotonia, an unsteady gait, osteoporosis, kyphoscoliosis and facial asymmetry. Transmission is X-linked recessive.
  • 序列相似性Belongs to the spermidine/spermine synthase family.
  • 结构域Composed of 3 domains: the N-terminal domain has structural similarity to S-adenosylmethionine decarboxylase, the central domain is made up of four beta strands and the C-terminal domain is similar in structure to spermidine synthase. The N- and C-terminal domains are both required for activity.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MRSR antibody
    • SMS antibody
    • Snyder Robinson X linked mental retardation syndrome antibody
    • Spermidine aminopropyltransferase antibody
    • Spermine synthase antibody
    • SPMSY antibody
    • SpS antibody
    • SPSY_HUMAN antibody
    • SRS antibody
    see all

Anti-Spermine synthase antibody 图像

  • All lanes : Anti-Spermine synthase antibody (ab101458) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : Jurkat whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 41 kDa

Anti-Spermine synthase antibody (ab101458)参考文献

ab101458 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab101458.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"