Anti-Spasmolytic Polypeptide抗体[GE16C] (ab49536)

概述

  • 产品名称Anti-Spasmolytic Polypeptide抗体[GE16C]
    参阅全部 Spasmolytic Polypeptide 一抗
  • 描述
    小鼠单克隆抗体[GE16C] to Spasmolytic Polypeptide
  • 经测试应用适用于: IHC-Pmore details
    不适用于: WB
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to a 16 amino acid C-terminal sequence of the human spasmolytic polypeptide.

  • 阳性对照
    • Human stomach and duodenum tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: Tissue culture supernatant
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号GE16C
  • 骨髓瘤P3-NS1/1-Ag4-1
  • 同种型IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab49536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.
    • 组织特异性Stomach.
    • 序列相似性Contains 2 P-type (trefoil) domains.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • SML 1 antibody
      • SML1 antibody
      • SP antibody
      • Spasmolysin antibody
      • Spasmolytic polypeptide antibody
      • spasmolytic protein 1 antibody
      • TFF 2 antibody
      • TFF2 antibody
      • TFF2_HUMAN antibody
      • trefoil factor 2 (spasmolytic protein 1) antibody
      • Trefoil factor 2 antibody
      • Trefoil factor 2 precursor antibody
      see all

    Anti-Spasmolytic Polypeptide antibody [GE16C] 图像

    • Immunohistochemical staining of paraffin embedded human stomach tissue, using ab49536 at 1/25 dilution, following antigen retrieval. 60 minutes primary antibody incubation at 25oC and standard ABC technique used. Note cytoplasmic staining of cardiac glands.

    Anti-Spasmolytic Polypeptide antibody [GE16C] (ab49536)参考文献

    This product has been referenced in:
    • Wu CS  et al. Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer. Int J Mol Sci 17:N/A (2016). Read more (PubMed: 27598141) »
    • Nam KT  et al. Gastric tumor development in Smad3-deficient mice initiates from forestomach/glandular transition zone along the lesser curvature. Lab Invest 92:883-95 (2012). Mouse . Read more (PubMed: 22411066) »

    See all 4 Publications for this product

    Product Wall

    Thank you for contacting us. I have placed the protocol below. Please let me know if you have any further questions.



    Cut and mount sections on slides coated with a suitable tissue adhesive.1.

    Deparaffinize sections and rehy...

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    This kit will work with mouse IgM antiobodies as well.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Free Rabbit monoc...

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    ab127055 kit can be used with any mouse antibody - this mean the kit would be suitable.

    Please note ab49536 is tested and guaranteed to be with mouse species however ab57752 is only tested with human sampl...

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    Thank you for your enquiry.

    According to the developer of the kit, the mouse-on-mouse IHC kit will be effective with IgM primary antibodies. The anti-Spamolytic Polypeptide antibody ab49536 is IgM isotype.

    Please contact us if you...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"