Anti-SPARC抗体(ab61383)

概述

  • 产品名称Anti-SPARC抗体
    参阅全部 SPARC 一抗
  • 描述
    小鼠单克隆抗体to SPARC
  • 特异性Recognises bone SPARC and platelet osteonectin
  • 经测试应用适用于: WB, ELISA, RIAmore details
  • 种属反应性
    与反应: Rat, Cow, Human
  • 免疫原

    Full length native purified Human SPARC

  • 表位First half of the N-terminus of the protein excluding the first 28 amino acids.

性能

应用

Our Abpromise guarantee covers the use of ab61383 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 35 kDa.
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

靶标

  • 功能Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
  • 序列相似性Belongs to the SPARC family.
    Contains 1 EF-hand domain.
    Contains 1 follistatin-like domain.
    Contains 1 Kazal-like domain.
  • 发展阶段Expressed at high levels in tissues undergoing morphogenesis, remodeling and wound repair.
  • 细胞定位Secreted > extracellular space > extracellular matrix > basement membrane. In or around the basement membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AA517111 antibody
    • Basement membrane protein 40 antibody
    • Basement-membrane protein 40 antibody
    • BM 40 antibody
    • BM-40 antibody
    • BM40 antibody
    • Cysteine rich protein antibody
    • hm:zeh0062 antibody
    • MGC128090 antibody
    • OI17 antibody
    • ON antibody
    • Osteonectin antibody
    • Secreted acidic cystein rich glycoprotein antibody
    • Secreted protein acidic and rich in cysteine antibody
    • Secreted protein acidic cysteine rich (osteonectin) antibody
    • Secreted protein acidic cysteine rich antibody
    • SPARC antibody
    • SPRC antibody
    • SPRC_HUMAN antibody
    see all

Anti-SPARC antibody (ab61383)参考文献

ab61383 has not yet been referenced specifically in any publications.

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Thank you for your reply.


After checking our records, I have found epitope information for both of these antibodies:


For ab13418: epitope includes the gamma-carboxylated residue at position 17
For ab61383: epitope i...

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