概述

  • 产品名称Anti-SOX6抗体
    参阅全部 SOX6 一抗
  • 描述
    兔多克隆抗体to SOX6
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 778-828 of Human SOX6 (EAW68458.1).

  • 阳性对照
    • 293T, HeLa and Jurkat whole cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab125196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 92 kDa.
IP Use at 2-10 µg/mg of lysate.

靶标

  • 功能Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.
  • 组织特异性Expressed in a wide variety of tissues, most abundantly in skeletal muscle.
  • 序列相似性Contains 1 HMG box DNA-binding domain.
  • 翻译后修饰Sumoylation inhibits the transcriptional activity.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HSSOX 6 antibody
    • HSSOX6 antibody
    • SOX 6 antibody
    • sox6 antibody
    • SOX6_HUMAN antibody
    • SOXD antibody
    • SRY (sex determining region Y) box 6 antibody
    • SRY box 6 antibody
    • SRY box containing gene 6 antibody
    • Transcription factor SOX 6 antibody
    • Transcription factor Sox-6 antibody
    • Transcription factor SOX6 antibody
    see all

Anti-SOX6 antibody 图像

  • All lanes : Anti-SOX6 antibody (ab125196) at 0.4 µg/ml

    Lane 1 : 293T whole cell lysate at 50 µg
    Lane 2 : 293T whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 50 µg
    Lane 4 : Jurkat whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 92 kDa


    Exposure time : 3 minutes
  • Detection of SOX6 by Western Blot of Immunprecipitate.
    ab125196 at 1µg/ml staining SOX6 in HeLa whole cell lysate immunoprecipitated using ab125196 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 10 seconds.

Anti-SOX6 antibody (ab125196)参考文献

ab125196 has not yet been referenced specifically in any publications.

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