Anti-SOX6抗体[155C5a] (ab84880)
Key features and details
- Mouse monoclonal [155C5a] to SOX6
- Suitable for: ICC/IF, WB
- Reacts with: Human, Recombinant fragment
- Isotype: IgG1
概述
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产品名称
Anti-SOX6抗体[155C5a]
参阅全部 SOX6 一抗 -
描述
小鼠单克隆抗体[155C5a] to SOX6 -
宿主
Mouse -
经测试应用
适用于: ICC/IF, WBmore details -
种属反应性
与反应: Human, Recombinant fragment -
免疫原
Recombinant fragment (Human) from the C-terminal end (Accession number: NM_033326)
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阳性对照
- HeLa cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Purified culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum. Sterile filtered through a 0.22 µm membrane. -
克隆
单克隆 -
克隆编号
155C5a -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab84880于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC/IF |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 93 kDa.
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说明 |
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ICC/IF
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 93 kDa. |
靶标
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功能
Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation. -
组织特异性
Expressed in a wide variety of tissues, most abundantly in skeletal muscle. -
序列相似性
Contains 1 HMG box DNA-binding domain. -
翻译后修饰
Sumoylation inhibits the transcriptional activity. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 55553 Human
- Omim: 607257 Human
- SwissProt: P35712 Human
- Unigene: 368226 Human
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别名
- HSSOX 6 antibody
- HSSOX6 antibody
- SOX 6 antibody
see all
图片
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Anti-SOX6 antibody [155C5a] (ab84880) + immunizing recombinant protein
Predicted band size: 93 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted?
The observed band size may not correspond to the predicted molecular weight as the recombinant immunogen was used for the test lane. -
Immunostaining analysis in HeLa cells using ab84880. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X 100 in PBS.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab84880 被引用在 4 文献中.
- Liu J et al. Salvianolic Acid B Protects Cardiomyocytes from Ischemia/Reperfusion Injury by Mediating circTRRAP/miR-214-3p/SOX6 Axis. Int Heart J 63:1176-1186 (2022). PubMed: 36450557
- Zhao Y et al. lncRNA PART1, manipulated by transcriptional factor FOXP2, suppresses proliferation and invasion in ESCC by regulating the miR-18a-5p/SOX6 signaling axis. Oncol Rep 45:1118-1132 (2021). PubMed: 33432363
- Long S et al. MicroRNA-765 is pregulated in multiple myeloma and serves an oncogenic role by directly targeting SOX6. Exp Ther Med 17:4741-4747 (2019). PubMed: 31105792
- Kinchen J et al. Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease. Cell 175:372-386.e17 (2018). PubMed: 30270042