Anti-SOSTDC1抗体(ab56079)

概述

  • 产品名称
    Anti-SOSTDC1抗体
    参阅全部 SOSTDC1 一抗
  • 描述
    兔多克隆抗体to SOSTDC1
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human SOSTDC1 (internal sequence).

  • 阳性对照
    • In Western Blot, this antibody gave a positive signal in human breast tissue lysate and in human, mouse and rat kidney tissue lysates.

性能

应用

Our Abpromise guarantee covers the use of ab56079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 23 kDa).
ELISA Use at an assay dependent dilution.

靶标

  • 功能
    May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
  • 组织特异性
    Highly expressed in kidney and weakly in lung.
  • 序列相似性
    Belongs to the sclerostin family.
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CDA019 antibody
    • DKFZp564D206 antibody
    • Ectodermal BMP inhibitor antibody
    • Ectodin antibody
    • sclerostin domain containing 1 antibody
    • Sclerostin domain containing protein 1 antibody
    • Sclerostin domain-containing protein 1 antibody
    • SOSD1_HUMAN antibody
    • Sostdc1 antibody
    • USAG-1 antibody
    • USAG1 antibody
    • Uterine sensitization associated gene 1 protein antibody
    • Uterine sensitization-associated gene 1 protein antibody
    • Wise antibody
    see all

图片

  • All lanes : Anti-SOSTDC1 antibody (ab56079) at 1 µg/ml

    Lane 1 : Human kidney tissue lysate - total protein (ab30203)
    Lane 2 : Human breast tissue lysate - total protein (ab30090)
    Lane 3 : Kidney (Mouse) Tissue Lysate
    Lane 4 : Kidney (Rat) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 23 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)


    Exposure time : 4 minutes

实验方案

文献

ab56079 has not yet been referenced specifically in any publications.

客户评价及客户问答

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunohistochemistry free floating
Sample
Mouse Tissue sections (E13.5 wild-type whole salivary gland)
Specification
E13.5 wild-type whole salivary gland
Username

Dr. Isabelle Miletich

Verified customer

提交于 Jun 04 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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