概述

  • 产品名称
  • 描述
    兔多克隆抗体to SORBS1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human, Chinese hamster
  • 免疫原

    Synthetic peptide corresponding to Human SORBS1 aa 869-896 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q9BX66

  • 阳性对照
    • MDA-MB231 cell line lysate CHO cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab107531 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 143 kDa.

靶标

  • 功能
    Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.
  • 组织特异性
    Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
  • 序列相似性
    Contains 3 SH3 domains.
    Contains 1 SoHo domain.
  • 翻译后修饰
    O-glycosylated.
  • 细胞定位
    Cell junction > adherens junction. Cell membrane. Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • c-Cbl-associated protein antibody
    • CAP antibody
    • CBL Associated Protein antibody
    • Ponsin antibody
    • SH3 domain protein 5 antibody
    • SH3D5 antibody
    • SH3P12 antibody
    • Sorbin and SH3 Domain Containing 1 antibody
    • Sorbin and SH3 domain-containing protein 1 antibody
    • Sorbs1 antibody
    • SRBS1_HUMAN antibody
    see all

图片

  • Anti-SORBS1 antibody (ab107531) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

    Predicted band size : 143 kDa
  • Anti-SORBS1 antibody (ab107531) at 1/100 dilution + CHO cell line lysate at 35 µg

    Predicted band size : 143 kDa

实验方案

文献

ab107531 has not yet been referenced specifically in any publications.

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