Anti-Sorbitol Dehydrogenase抗体(ab66065)

概述

  • 产品名称Anti-Sorbitol Dehydrogenase抗体
    参阅全部 Sorbitol Dehydrogenase 一抗
  • 描述
    小鼠单克隆抗体to Sorbitol Dehydrogenase
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Cow, Chimpanzee, Cynomolgus Monkey, Rhesus monkey, Orangutan
  • 免疫原

    Recombinant tagged fragment: MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR, corresponding to amino acids 1-111 of Human Sorbitol Dehydrogenase

  • 阳性对照
    • Hela nuclear extract.

性能

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应用

Our Abpromise guarantee covers the use of ab66065 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution. Sandwich ELISA: The detection limit for recombinant tagged Sorbitol Dehydrogenase is approximately 0.1ng/ml as a capture antibody.
    WB: Use at a concentration of 1 - 5 µg/ml. Detects a band of approximately 36 kDa (predicted molecular weight: 38 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm.
    • 组织特异性Expressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level).
    • 序列相似性Belongs to the zinc-containing alcohol dehydrogenase family.
    • 细胞定位Mitochondrion membrane. Cell projection > cilium > flagellum. Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DHSO_HUMAN antibody
      • L iditol 2 dehydrogenase antibody
      • L-iditol 2-dehydrogenase antibody
      • OTTHUMP00000161939 antibody
      • SDH antibody
      • Sorbitol dehydrogenase 1 antibody
      • Sorbitol dehydrogenase antibody
      • SORD 1 antibody
      • SORD antibody
      • SORD1 antibody
      see all

    Anti-Sorbitol Dehydrogenase antibody 图像

    • Anti-Sorbitol Dehydrogenase antibody (ab66065) at 1 µg/ml + HeLa nuclear extract at 50 µg

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

      Predicted band size : 38 kDa
      Observed band size : 36 kDa (why is the actual band size different from the predicted?)

    Anti-Sorbitol Dehydrogenase antibody (ab66065)参考文献

    ab66065 has not yet been referenced specifically in any publications.

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